Atopic dermatitis (AD) is a complex inflammatory skin condition that is not fully understood.Epidermal barrier defects and Th2 immune response dysregulations are thought to play crucial roles in the pathogenesis of the disease.A vicious circle takes place between these alterations, and it can further be complicated by additional genetic and environ
The identification of autoantigens remains a critical challenge for understanding and treating autoimmune diseases.Autoimmune polyendocrine syndrome type 1 (APS1), a rare monogenic form of autoimmunity, presents as widespread autoimmunity with T and B cell responses Sphere Rigs to multiple organs.Importantly, autoantibody discovery in APS1 can illu
The present study numerically describes the nature of the arising boundary layer along an isothermal vertical plate, on which is mounted a bluff body.The investigation parameter is the cross-section shape of the bluff body, which includes a square, circular, and prismatic cylinders.To entirely embedded cylinder in the incoming boundary layer, the s
BackgroundAbnormalities of the mitral valve (MV) apparatus are typical features of hypertrophic cardiomyopathy (HCM).These abnormalities include leaflet elongation, thick leaflets, displacement of papillary muscle, and systolic anterior motion (SAM) of the MV anterior leaflet.Mitral valve chordal rupture associated with HCM is a rare but serious is
Operational risk has been acknowledged as a major source of material failures in financial firms.Despite the increased concern of financial institutions and their stakeholders on this topic, the literature that deals specifically with the operational risk disclosure in the banking system is scarce.The present research investigates the readability i